Since last six months I removed following codes with my OBD-2 many times but they come back.I replaced with new gas cap.no difference.
Toyota camry 4 cylndr 2000, 150000km.Codes are
P0401
P0441
P0446
Please help me.

Ah ha!!! Another one who hasn't looked at the FAQ thread at the top of the forum. Not to worry. You've got plenty of company.

Open the FAQs thread titled "Camry FAQS..." and scroll down about one third of the first page. You'll start seeing a llllloooonnnngggg list of codes. Those codes that are in bold type have troubleshooting tips listed and guess what? All of your codes are in bold type. Keep scrolling past the list and you'll start seeing the troubleshooting info listed with their codes. Keep scrolling till you find your codes. Cheers!

sounds like the vsv for the charcoal canister by the gas tank

replace the vsv i think it cost $60 from the dealer

and clear the code and that should fix your problem