I have an '02 Blazer and the engine seems to sputter at various times when I am driving. It is especially noticable when I have come to a complete stop, then accelerate slowly...it will feel like the truck is jerking a little bit. It will happen between 10-15mph, but when I get my speed up above 20-25mph or so, the truck drives pretty smooth. However, I also notice it around 60 mph, a slight sputtering/jerking feeling.

Fuel pump going bad?
Clogged injectors?

Needs proper testing to find out.
What is mileage and and tune yup history?
Any check engine lights on or blinking?
Have you checked fuel filter and fuel pressure?