does anyone know if it is possible to put a pontiac 350 motor in a 93 cherokke, and if so will i need to change the transmission or what, i have a 350 pontuiac and a cherokke with a blown inline 6. thanks for your help.

anything is possible. Chevy 350 blocks find themselves installed in Jeeps all the time. Enough that i bet there is some company that makes this swap easy.

Try:
http://www.novak-adapt.com/knowledge/xj_swap.htm

If you do that, fine, but make sure you use the ecu that comes with that engine.