I have a 2000 blazer 2wd I just recently gave it a tune up because I am having trouble accelerating. It starts fine but when I hit the gas it hesitates for a minute like it doesn't want to go and then picks up and it runs fine I was wondering if it could have something to do with the coil pack, compression, or something else far worse.

What did the tuneup include?

I changed the oil, oil filter, air filter, new wires, plugs, distributer cap and button, added fuel injector cleaner, and oil treatment, recently replaced catalytic converter, checked vacuum hoses

Swap out your fuel filter too...

Yip, replace the fuel filter, PCV valve.

Also, what plugs did you use and what gap?