I might be making a long trip on the high way 3-5 hours on my blizzaks *depending on weather* will this be safe i hear yes and no could someone clear it up please.

thanks a ton

yes, it is safe, but it does wear them out.

They will be fine as long as you will not be driving into a warmer area (above 50 degrees). I've driven on 80/90 between South Bend and Chicago in my wife's Windstar on Blizzaks with no issues.